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Table 3 Parameters of circadian rhythms of sodium nitroprusside-induced motor incoordination in 8 week old mice

From: Time-of-day dependence of neurological deficits induced by sodium nitroprusside in young mice

Dose
(mg/kg)
Gender Period
τ (h)
Mesor ±
SEM (% of ataxia)
Amplitude ± SD
(% of ataxia)
Acrophase
± SD (min)b
Adjusted P a
  Male 12 35 ± 4 8 0.42 NS
3.0   24 34 ± 4 18 ± 14 3.2 ± 108 NS
  Female 12 27 ± 4 8 2.8 NS
   24 27 ± 4 14 ± 13 2.7 ± 78 NS
   12 27 ± 4 8 2.7 NS
3.3 Male 24 26 ± 4 14 ± 12 2.0 ± 60 NS
   12 19 ± 3 3 4.5 NS
  Female 24 20 ± 3 11 ± 10 1.3 ± 90 NS
   12 41 ± 4 6 3.1 NS
3.6   24 40 ± 4 23 ± 13 3.4 ± 120 0.003
  Male 12 19 ± 3 8 1.9 NS
  Female 24 19 ± 3 20 ± 10 2.1 ± 55 0.003
  1. a From an F test of the rejection of the null amplitude hypothesis.
  2. b Time of maximum in fitted cosine function, in HALO.
  3. NS: Not significant