Table 2 Parameters of ultradian and circadian rhythms of sodium nitroprusside-induced motor incoordination in 4 week old mice
From: Time-of-day dependence of neurological deficits induced by sodium nitroprusside in young mice
|
Dose (mg/kg) | Gender |
Period τ (h) |
Mesor ± SEM (% of ataxia) |
Amplitude ± SD (% of ataxia) |
Acrophase ±SD (min)b | Adjusted P a |
|---|---|---|---|---|---|---|
| Male | 12 | 30 ± 4 | 15 ± 14 | 1.1 ± 120 | NS | |
| 3.0 | 24 | 28 ± 4 | 2 | 5.4 | NS | |
| Female | 12 | 33 ± 4 | 15 ± 14 | 1.2 ± 120 | NS | |
| 24 | 33 ± 4 | 12 | 3.2 | NS | ||
| 12 | 49 ± 5 | 26 ± 17 | 1.9 ± 74 | NS | ||
| 3.3 | Male | 24 | 40 ± 4 | 10 | 8.8 | NS |
| 12 | 31 ± 5 | 17 ± 16 | 1.4 ± 120 | NS | ||
| Female | 24 | 32 ± 5 | 2 | 1.5 | NS | |
| 12 | 65 ± 4 | 18 ± 13 | 1.2 ± 90 | NS | ||
| 3.6 | 24 | 64 ± 4 | 16 ± 13 | 4.5 ± 228 | NS | |
| Male | 12 | 36 ± 5 | 16 ± 15 | 2.0 ± 120 | NS | |
| Female | 24 | 34 ± 3 | 4 | 5.0 | NS |