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Baseline
|
Study End (3 months)
|
% change
|
Unpaired t test (df = 67)
|
Paired t test (df = 22)
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Paired t test (df = 45)
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Unpaired t test (df = 67)
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|---|
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Item No.
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Description
|
Control (n = 23)
|
Intervention (n = 46)
|
Control (n = 23)
|
Intervention (n = 46)
|
Control
|
Intervention
|
Baseline comparison
|
Control change
|
Intervention change
|
3 month comparison
|
|---|
| | |
mean (SD)
|
mean (SD)
|
mean (SD)
|
mean (SD)
| | |
t statistic
|
t statistic
|
t statistic
|
t statistic
|
|---|
|
1
|
Fatigue/tiring easily?
|
2.9 (0.9)
|
2.9 (1.1)
|
2.7 (1.1)
|
2.1 (1.0)
|
7.6
|
26.9
|
-0.16
|
0.93
|
4.04**
|
1.76
|
|
2
|
Trouble concentrating
|
2.5 (1.1)
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2.9 (1.2)
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2.5 (0.9)
|
1.8 (0.9)
|
1.7
|
36.8
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-1.23
|
0.21
|
5.84**
|
3.46*
|
|
3
|
Physical clumsiness?
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2.0 (1.1)
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1.7 (1.0)
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1.6 (0.6)
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1.5 (0.9)
|
21.7
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13.7
|
1.02
|
1.93
|
1.48
|
-0.70
|
|
4
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Decreased daytime alertness?
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2.7 (1.1)
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2.5 (1.2)
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2.1 (0.8)
|
1.8 (0.8)
|
21.0
|
28.1
|
0.74
|
2.73
|
3.96**
|
0.45
|
|
5
|
Trouble with memory?
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2.4 (1.3)
|
1.9 (1.1)
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2.1 (0.8)
|
1.5 (0.7)
|
12.5
|
21.3
|
1.65
|
1.07
|
2.80
|
0.38
|
|
6
|
General feelings of weakness
|
2.0 (1.1)
|
2.0 (1.0)
|
1.7 (0.7)
|
1.4 (0.8)
|
17.0
|
26.7
|
0.33
|
1.56
|
3.60*
|
0.67
|
|
7
|
Light-headed & dizzy
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2.2 (1.4)
|
2.1 (1.3)
|
2.0 (1.1)
|
1.4 (0.8)
|
9.8
|
33.7
|
0.26
|
1.10
|
4.04**
|
1.74
|
|
8
|
Lethargy/sluggish feelings?
|
3.0 (1.0)
|
2.7 (1.3)
|
2.3 (0.8)
|
1.8 (0.8)
|
23.5
|
31.7
|
0.93
|
3.43*
|
5.07**
|
0.55
|
|
9
|
Sleepiness in day
|
3.0 (1.2)
|
2.8 (1.2)
|
2.6 (1.0)
|
1.9 (0.7)
|
14.5
|
31.0
|
0.66
|
2.47
|
4.90**
|
1.55
|
|
10
|
Work performance
|
7.0 (1.7)
|
6.4 (1.5)
|
7.3 (1.6)
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7.6 (1.4)
|
4.4
|
19.4
|
1.45
|
-1.16
|
-6.07**
|
-2.72
|
|
11
|
Alertness and concentration
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6.2 (1.8)
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6.1 (1.9)
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6.8 (1.7)
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7.5 (1.8)
|
9.9
|
22.9
|
0.23
|
-2.13
|
-4.34**
|
-1.57
|
| |
Combined Score (first 9 items)
|
22.7 (7.5)
|
21.5 (8.3)
|
19.5 (5.2)
|
15.4 (5.7)
|
14.3
|
28.6
|
0.59
|
2.60
|
5.22**
|
1.53
|
- * = p < 0.05, ** = p < 0.001 equivalent after applying Bonferroni correction
